INTS6 Antibody

• Background:

  DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH) . Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  26512

• Swiss Prot:

  Q9UL03

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human INTS6 (NP_036273.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 115kDa

• Fragment:

  IgG

• Symbol:

  INTS6

• Positive Control 2:

  SW620

• Positive Control 3:

  HeLa

• Positive Control 4:

  NCI-H460

• Positive Control 5:

  U-251MG

• NCBI Official Name:

  Integrator complex subunit 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2, integrator complex subunit 6, DEAD box protein, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26, RNA helicase HDB, protein deleted in cancer 1

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid