INTS1 Antibody

• Background:

  INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]) .

• NCBI Gene ID:

  26173

• Swiss Prot:

  Q8N201

• Accession Number:

  Q8N201

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This INTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human INTS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  244 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  INTS1

• NCBI Official Name:

  Integrator complex subunit 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nusbaum, C., et al. Nature 439 (7074) :331-335 (2006)

• Background Reference 02:

  Baillat, D., et al. Cell 123 (2) :265-276 (2005)

• Background Reference 03:

  Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

• Other Product Names:

  Integrator complex subunit 1, Int1, INTS1, KIAA1440

• Tested Applications:

  WB

• Protein ID:

  97052424

• Physical Properties:

  Liquid