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HSD11B2 Antibody

CAT: 0223-25-696Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-696Size:100 µL
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Background
HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
NCBI Gene ID
3291
Swiss Prot
P80365
Accession Number
NP_000187
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSD11B2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
HSD11B2 antibody can be used for detection of HSD11B2 by ELISA at 1:62500. HSD11B2 antibody can be used for detection of HSD11B2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HSD11B2
NCBI Official Name
Hydroxysteroid (11-beta) dehydrogenase 2
NCBI Organism
Homo sapiens
Background Reference 01
Hovanessian, A.G., (2008) Mol. Cell. Biol. 28 (11), 3830-3849.
Other Product Names
HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3
Tested Applications
ELISA, WB
Protein ID
119392083
Physical Properties
Liquid

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