HSD11B2 Antibody

• Background :

  HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

• NCBI Gene ID :

  3291

• Swiss Prot :

  P80365

• Accession Number :

  NP_000187

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSD11B2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  45 kDa

• Applications Notes :

  HSD11B2 antibody can be used for detection of HSD11B2 by ELISA at 1:62500. HSD11B2 antibody can be used for detection of HSD11B2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  HSD11B2

• NCBI Official Name :

  Hydroxysteroid (11-beta) dehydrogenase 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Hovanessian, A.G., (2008) Mol. Cell. Biol. 28 (11), 3830-3849.

• Other Product Names :

  HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3

• Tested Applications :

  ELISA, WB

• Protein ID :

  119392083

• Physical Properties :

  Liquid