MARCH7 Antibody

• Background:

  MARCH7 is an E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

• NCBI Gene ID:

  64844

• Swiss Prot:

  Q9H992

• Accession Number:

  NP_073737

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Homeostasis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1309 - Human Placenta Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MARCH7 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  78 kDa

• Applications Notes:

  MARCH7 antibody can be used for detection of 40244 by ELISA at 1:62500. MARCH7 antibody can be used for detection of 40244 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MARCH7

• NCBI Official Name:

  Membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Muthukumarana, P.A., Int. Immunopharmacol. 6 (13-14), 1993-2001 (2006) .

• Other Product Names:

  MARCH7, AXO, AXOT, DKFZP586F1122, MARCH-VII, RNF177

• Tested Applications:

  ELISA, WB

• Protein ID:

  12383066

• Physical Properties:

  Liquid