SYMPK Antibody

SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

8189

Q92797

NP_004810

Human

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SYMPK.

Unconjugated

Primary Antibodies

Homeostasis

Antibody is purified by peptide affinity chromatography method.

Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SYMPK antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

141 kDa

SYMPK antibody can be used for detection of SYMPK by ELISA at 1:1562500. SYMPK antibody can be used for detection of SYMPK by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

SYMPK

Symplekin

Homo sapiens

Cao, Y., (2007) Histopathology 51 (4), 528-538.

SYMPK, FLJ27092, SPK, SYM

ELISA, WB

124028529