MSH5 Antibody

• Background:

  MSH5 is a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4.This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar to a Saccharomyces cerevisiae protein that participates in meiotic segregation fidelity and crossing-over. This protein forms heterooligomers with another member of this family, mutS homolog 4. Alternative splicing results in four transcript variants encoding three different isoforms.

• NCBI Gene ID:

  4439

• Swiss Prot:

  Q9UMP2

• Accession Number:

  NP_079535

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSH5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MSH5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  95 kDa

• Applications Notes:

  MSH5 antibody can be used for detection of MSH5 by ELISA at 1:312500. MSH5 antibody can be used for detection of MSH5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MSH5

• NCBI Official Name:

  MutS homolog 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bethke, L., (2008) J. Natl. Cancer Inst. 100 (4), 270-276.

• Other Product Names:

  MSH5, DKFZp434C1615, G7, MGC2939, MutSH5, NG23, MUTSH5

• Tested Applications:

  ELISA, WB

• Protein ID:

  262231786

• Physical Properties:

  Liquid