MSH2 Antibody

• Background:

  This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  4436

• Swiss Prot:

  P43246

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human MSH2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 150kDa

• Fragment:

  IgG

• Symbol:

  MSH2

• NCBI Official Name:

  MutS homolog 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MSH2, FCC1, COCA1, HNPCC, LCFS2, HNPCC1

• Tested Applications:

  WB, IF, Flow

• Physical Properties:

  Liquid