MSH2 Antibody

CAT: 0223-55-920Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-920Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq].
NCBI Gene ID
4436
Swiss Prot
P43246
Accession Number
P43246
Host
Rabbit
Reactivity
Human
Immunogen
This MSH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the Central region of human MSH2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Symbol
MSH2
NCBI Official Name
DNA mismatch repair protein Msh2
NCBI Organism
Homo sapiens
Background Reference 01
Kim, M., et al. Cancer Sci. 101 (11) :2436-2442 (2010)
Background Reference 02
Mangoni, M., et al. Int. J. Radiat. Oncol. Biol. Phys. (2010) In press :
Background Reference 03
Srivastava, K., et al. Cancer 116 (13) :3160-3169 (2010)
Background Reference 04
Van der Post, R.S., et al. J. Med. Genet. 47 (7) :464-470 (2010)
Other Product Names
DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2, MSH2
Tested Applications
WB, IF, Flow
Protein ID
1171032
Physical Properties
Liquid

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