MLLT3 Antibody

• Background:

  MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22; q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.

• NCBI Gene ID:

  4300

• Swiss Prot:

  P42568

• Accession Number:

  NP_004520

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLLT3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MLLT3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  63 kDa

• Applications Notes:

  MLLT3 antibody can be used for detection of MLLT3 by ELISA at 1:1562500. MLLT3 antibody can be used for detection of MLLT3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  MLLT3

• NCBI Official Name:

  Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wei, J., (2008) Cancer Cell 13 (6), 483-495.

• Other Product Names:

  MLLT3, AF9, FLJ2035, YEATS3

• Tested Applications:

  ELISA, WB

• Protein ID:

  156104889

• Physical Properties:

  Liquid