PGAM2 Antibody

• Background:

  Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB) . This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.

• NCBI Gene ID:

  5224

• Swiss Prot:

  P15259

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human PGAM2 (NP_000281.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 29kDa

• Fragment:

  IgG

• Symbol:

  PGAM2

• Positive Control 2:

  SH-SY5Y

• Positive Control 3:

  U-87MG

• Positive Control 4:

  Mouse kidney

• Positive Control 5:

  Mouse testis

• Positive Control 6:

  Mouse skeletal muscle

• NCBI Official Name:

  Phosphoglycerate mutase 2 (muscle)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PGAM2, MGC88743, PGAMM, GSD10, PGAM-M

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid