ITPR1 Antibody

• Background:

  This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

• NCBI Gene ID:

  3708

• Swiss Prot:

  Q14643

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1850-1950 of human ITPR1 (XP_011531985.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 315kDa

• Fragment:

  IgG

• Symbol:

  ITPR1

• Positive Control 2:

  HT-1080

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Mouse brain

• NCBI Official Name:

  Inositol 1,4,5-trisphosphate receptor, type 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ITPR1, InsP3R-I, IP3R1, InsP3R, InsP3R type I, INSP3R1, IP3R, Opisthotonus, Pcp1, IP3 receptor, IP3 receptor isoform 1, SCA15, Spinocerebellar ataxia 15, Spinocerebellar ataxia 16, I145TR, IP3R 1, SCA16, Type 1 InsP3 receptor

• Tested Applications:

  WB, IHC, IF, IP

• Physical Properties:

  Liquid