ITPR3 Antibody

• Background :

  This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

• NCBI Gene ID :

  3710

• Swiss Prot :

  Q14573

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 (NP_002215.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 300kDa

• Fragment :

  IgG

• Symbol :

  ITPR3

• Positive Control 2 :

  LO2

• Positive Control 3 :

  HepG2

• NCBI Official Name :

  Inositol 1,4,5-trisphosphate receptor, type 3

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  ITPR3, inositol 1, 4, 5-triphosphate receptor, type 3, HGNC:6182, FLJ36205, IP3R, IP3R3

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid