ITPR3 Antibody

• Background:

  This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

• NCBI Gene ID:

  3710

• Swiss Prot:

  Q14573

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1870 of human ITPR3 (NP_002215.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 300kDa

• Fragment:

  IgG

• Symbol:

  ITPR3

• Positive Control 2:

  LO2

• Positive Control 3:

  HepG2

• NCBI Official Name:

  Inositol 1,4,5-trisphosphate receptor, type 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ITPR3, inositol 1, 4, 5-triphosphate receptor, type 3, HGNC:6182, FLJ36205, IP3R, IP3R3

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid