BPGM Antibody

• Background:

  2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• NCBI Gene ID:

  669

• Swiss Prot:

  P07738

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human BPGM (NP_001715.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 30kDa

• Fragment:

  IgG

• Symbol:

  BPGM

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse liver

• Positive Control 5:

  Mouse spleen

• Positive Control 6:

  Mouse testis

• NCBI Official Name:

  Bisphosphoglycerate mutase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Bisphosphoglycerate mutase, BPGM,3-bisphosphoglycerate mutase, erythrocyte,3-bisphosphoglycerate synthase,3-diphosphoglycerate mutase, DPGM, BPG-dependent PGAM, BPGM

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid