SETDB2 Antibody

• Background :

  This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  83852

• Swiss Prot :

  Q96T68

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SETDB2 (NP_001153780.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  HL-60

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 82kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  SETDB2

• Positive Control 2 :

  Mouse thymus

• Positive Control 3 :

  Rat heart

• NCBI Official Name :

  SET domain, bifurcated 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Histone-lysine N-methyltransfera, chronic lymphocytic leukemia deletion region gene 8 protein, OTTHUMP00000018418, KMT1F, DKFZp761J1217, DKFZp586I0123, CLLL8, CLLD8, C13orf4, SET domain, bifurcated 2, SETDB2

• Tested Applications :

  WB

• Physical Properties :

  Liquid