SETDB1 Antibody

• Background :

  This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

• NCBI Gene ID :

  9869

• Swiss Prot :

  Q15047

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-397 of human SETDB1 (NP_001230420.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 210kDa

• Fragment :

  IgG

• Symbol :

  SETDB1

• Positive Control 2 :

  MCF7

• Positive Control 3 :

  DU145

• Positive Control 4 :

  HL-60

• Positive Control 5 :

  Jurkat

• Positive Control 6 :

  293T

• NCBI Official Name :

  SET domain, bifurcated 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  SETDB1, H3-K9-HMTase4, ESET, KMT1E, H3-K9-HMTase 4, KG1T, SET domain, bifurcated 1, SET domain bifurcated 1, KIAA0067, Lysine N-methyltransferase 1E

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid