SETDB1 Antibody

• Background:

  This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

• NCBI Gene ID:

  9869

• Swiss Prot:

  Q15047

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-397 of human SETDB1 (NP_001230420.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 210kDa

• Fragment:

  IgG

• Symbol:

  SETDB1

• Positive Control 2:

  MCF7

• Positive Control 3:

  DU145

• Positive Control 4:

  HL-60

• Positive Control 5:

  Jurkat

• Positive Control 6:

  293T

• NCBI Official Name:

  SET domain, bifurcated 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SETDB1, H3-K9-HMTase4, ESET, KMT1E, H3-K9-HMTase 4, KG1T, SET domain, bifurcated 1, SET domain bifurcated 1, KIAA0067, Lysine N-methyltransferase 1E

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid