RNF7 Antibody

• Background :

  The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII) . The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1 (CDKN1B) . Alternatively spliced transcript variants encoding distinct isoforms have been reported.

• NCBI Gene ID :

  9616

• Swiss Prot :

  Q9UBF6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cell Cycle

• Purification :

  Affinity purification

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Fragment :

  IgG

• Symbol :

  RNF7

• NCBI Official Name :

  Ring finger protein 7

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  RNF7, zinc RING finger protein SAG, sensitive to apoptosis, regulator of cullins 2, OTTHUMP00000180645, SAG, ROC2, CKBBP1, ring finger protein 7, RNF7, RBX2

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid