APLP1 Antibody

• Background:

  This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

• NCBI Gene ID:

  333

• Swiss Prot:

  P51693

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 39-300 of human APLP1 (NP_005157.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 68kDa

• Fragment:

  IgG

• Symbol:

  APLP1

• Positive Control 2:

  HeLa

• Positive Control 3:

  SH-SY5Y

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse stomach

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Amyloid beta precursor like protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  APLP, amyloid-like protein 1, amyloid beta (A4) precursor-like protein 1, amyloid precursor-like protein 1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid