APLP2 (phospho Tyr755) Antibody

• Background:

  APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3' (CDEI box) .

• NCBI Gene ID:

  334

• Swiss Prot:

  Q06481

• Accession Number:

  NP_001633.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  APLP2 (phospho Tyr755) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y (p) -K-Y) derived from Human APLP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  86 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755

• Symbol:

  APLP2

• NCBI Official Name:

  Amyloid beta (A4) precursor-like protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sprecher C.A., Biochemistry 32:4481-4486 (1993) .

• Background Reference 02:

  Wasco W., Nat. Genet. 5:95-99 (1993) .

• Background Reference 03:

  Von der Kammer H., DNA Cell Biol. 13:1137-1143 (1994) .

• Other Product Names:

  Amyloid protein homolog , Amyloid-like protein 2 precursor, APP2, APPH, CDEI-box binding protein

• Tested Applications:

  IHC

• Protein ID:

  214010181

• Physical Properties:

  Liquid