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SPHK2 Antibody

CAT: 0223-22-458Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-458Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
56848
Swiss Prot
Q9NRA0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human SPHK2 (NP_001191088.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 73kDa
Fragment
IgG
Symbol
SPHK2
NCBI Official Name
Sphingosine kinase 2
NCBI Organism
Homo sapiens
Other Product Names
SPHK2, SK-2, Sk2, Sphingosine kinase type 2, SPK-2, Sphingosine kinase 2, SPHK2L, SK 2, SPK 2
Tested Applications
WB, IHC
Physical Properties
Liquid

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