RECK Antibody

• Background:

  The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  8434

• Swiss Prot:

  O95980

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 110-210 of human RECK (NP_066934.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 106kDa

• Fragment:

  IgG

• Symbol:

  RECK

• Positive Control 2:

  MCF-7

• Positive Control 3:

  H460

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse kidney

• NCBI Official Name:

  Reversion-inducing cysteine-rich protein with Kazal motifs

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK, ST15

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid