PYGB Antibody

• Background :

  The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.

• NCBI Gene ID :

  5834

• Swiss Prot :

  P11216

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 544-843 of human PYGB (NP_002853.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  BT-474

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 105kDa

• Fragment :

  IgG

• Symbol :

  PYGB

• Positive Control 2 :

  SW620

• Positive Control 3 :

  HT-29

• Positive Control 4 :

  HepG2

• Positive Control 5 :

  Mouse brain

• Positive Control 6 :

  Mouse heart

• NCBI Official Name :

  Phosphorylase, glycogen; brain

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PYGB, GPBB, Phosphorylase, glycogen, Phosphorylase, glycogen brain, Glycogen phosphorylase B

• Tested Applications :

  WB, IF, IP

• Physical Properties :

  Liquid