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PYGM Antibody

CAT: 0223-57-778Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-778Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.
NCBI Gene ID
5837
Swiss Prot
P11217
Accession Number
P11217
Host
Rabbit
Reactivity
Human
Immunogen
This PYGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-727 amino acids from the C-terminal region of human PYGM.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
97 kDa
Fragment
Rabbit Ig
Symbol
PYGM
NCBI Official Name
Glycogen phosphorylase, muscle form
NCBI Organism
Homo sapiens
Background Reference 01
Tsoi, S.C., et al., J. Soc. Gynecol. Investig. 10 (8) :496-502 (2003) .
Background Reference 02
Bruno, C., et al., Neuromuscul. Disord. 12 (5) :498-500 (2002) .
Background Reference 03
Hadjigeorgiou, G.M., et al., Neuromuscul. Disord. 12 (9) :824-827 (2002) .
Background Reference 04
Deschauer, M., et al., Mol. Genet. Metab. 74 (4) :489-491 (2001) .
Other Product Names
Glycogen phosphorylase, muscle form, Myophosphorylase, PYGM
Tested Applications
WB, IHC-P
Protein ID
3041717
Physical Properties
Liquid

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