PCBD1 Antibody

• Background:

  This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  5092

• Swiss Prot:

  P61457

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human PCBD1 (NP_000272.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SW620

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 12kDa

• Fragment:

  IgG

• Symbol:

  PCBD1

• Positive Control 2:

  Mouse liver

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Mouse pancreas

• Positive Control 5:

  Rat liver

• NCBI Official Name:

  Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PCBD1, DCOH, PCBD, PCD, PHS

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid