CYP2C9 Antibody

• Background:

  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

• NCBI Gene ID:

  1559

• Swiss Prot:

  P11712

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 211-490 of human CYP2C9 (NP_000762.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 63kDa

• Fragment:

  IgG

• Symbol:

  CYP2C9

• Positive Control 2:

  MCF7

• Positive Control 3:

  U-937

• Positive Control 4:

  HepG2

• Positive Control 5:

  22Rv1

• Positive Control 6:

  Raji

• NCBI Official Name:

  Cytochrome P450, family 2, subfamily C, polypeptide 9

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CYP2C9, CPC9, CYP2C, CYP2C10, MGC149605, MGC88320, P450 MP-4, P450 PB-1, P450IIC9, CYPIIC9

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid