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JNJ-63533054

CAT: 0498-bs-82716C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82716C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and selective brain-penetrant GPR139 agonist (EC50=16 nM) an orphan G-protein-coupled receptor expressed in the CNS.1 Tritium-labeled JNJ-63533054 binds to cell membranes expressing GPR139 and can be displaced by putative endogenous ligands.2 Decreases compulsive-like alcohol drinking and hyperalgesia in alcohol-dependent rodents.3 Suppresses morphine intake in a mouse self-administration model.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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