CTCFL Antibody

• Background :

  CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  140690

• Swiss Prot :

  Q8NI51

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CTCFL (NP_001255970.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Transcription

• Purification :

  Affinity purification

• Positive Control :

  Jurkat

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 68kDa

• Fragment :

  IgG

• Symbol :

  CTCFL

• Positive Control 2 :

  HeLa

• Positive Control 3 :

  Mouse heart

• Positive Control 4 :

  Rat testis

• NCBI Official Name :

  CCCTC-binding factor (zinc finger protein) -like

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CTCFL, CT27, BORIS, CTCF-T, HMGB1L1, dJ579F20.2

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid