CREM Antibody

• Background:

  This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

• NCBI Gene ID:

  1390

• Swiss Prot:

  Q03060

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CREM (NP_853549.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction, Transcription

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 39kDa

• Fragment:

  IgG

• Symbol:

  CREM

• Positive Control 2:

  K-562

• Positive Control 3:

  Mouse testis

• Positive Control 4:

  Rat testis

• NCBI Official Name:

  CAMP responsive element modulator

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CREM, ICER, CREM-2, hCREM-2, RP11-324I22.3

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid