GLRX Antibody

• Background:

  This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

• NCBI Gene ID:

  2745

• Swiss Prot:

  P35754

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human GLRX (NP_001112362.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  SW480

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 12kDa

• Fragment:

  IgG

• Symbol:

  GLRX

• Positive Control 2:

  NCI-H460

• NCBI Official Name:

  Glutaredoxin (thioltransferase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DRK1, KCB1, KCNB1, Potassium channel Kv2.1, Potassium voltage-gated channel subfamily B member 1

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid