COTL1 Antibody

• Background :

  This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

• NCBI Gene ID :

  23406

• Swiss Prot :

  Q14019

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human COTL1 (NP_066972.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  Jurkat

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 14kDa

• Fragment :

  IgG

• Symbol :

  COTL1

• Positive Control 2 :

  293T

• Positive Control 3 :

  U-251MG

• Positive Control 4 :

  HeLa

• Positive Control 5 :

  Mouse lung

• Positive Control 6 :

  Mouse kidney

• NCBI Official Name :

  Coactosin-like protein

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Coactosin-like protein, COTL1, CLP

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid