COTL1 Antibody

• Background:

  This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

• NCBI Gene ID:

  23406

• Swiss Prot:

  Q14019

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human COTL1 (NP_066972.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 14kDa

• Fragment:

  IgG

• Symbol:

  COTL1

• Positive Control 2:

  293T

• Positive Control 3:

  U-251MG

• Positive Control 4:

  HeLa

• Positive Control 5:

  Mouse lung

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Coactosin-like protein

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Coactosin-like protein, COTL1, CLP

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid