COTL1 Antibody

• Background:

  COTL1 is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis.

• NCBI Gene ID:

  23406

• Swiss Prot:

  Q14019

• Accession Number:

  Q14019

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This COTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-142 amino acids from the C-terminal region of human COTL1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  COTL1

• NCBI Official Name:

  Coactosin-like protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Provost, P., et.al., Proc. Natl. Acad. Sci. U.S.A. 96 (5), 1881-1885 (1999)

• Background Reference 02:

  Provost, P., et.al., J. Biol. Chem. 276 (19), 16520-16527 (2001)

• Other Product Names:

  Coactosin-like protein, COTL1, CLP

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  21759076

• Physical Properties:

  Liquid