COTL1 antibody

• Background :

  Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.

• Synonyms :

  Coactosin-like protein|COTL1|CLP

• Gene ID :

  23406

• UniProt :

  Q14019

• Host :

  Mouse

• Reactivity :

  Human, Mouse

• Immunogen :

  Coactosin-like 1

• Target :

  COTL1

• Clonality :

  Monoclonal

• Isotype :

  IgG1

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Signal Transduction

• Purification :

  Protein A+G purification

• Dilution :

  WB: 1:1000-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  16 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID :

  6H5

• Tested Applications :

  ELISA, WB, IHC, IF

• Immunogen Sequence :

  1-142aa