SOS1 Antibody

• Background:

  This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.

• NCBI Gene ID:

  6654

• Swiss Prot:

  Q07889

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1034-1333 of human SOS1 (NP_005624.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 175kDa/200kDa

• Fragment:

  IgG

• Symbol:

  SOS1

• Positive Control 2:

  Mouse liver

• Positive Control 3:

  Rat brain

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  Son of sevenless homolog 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Son of sevenless homolog 1, SOS-1, SOS1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid