AKT2 Antibody [8G3B6], KO Validated

• Background:

  This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

• NCBI Gene ID:

  208

• Swiss Prot:

  P31751

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Recombinant protein of human AKT2

• Clonality:

  Monoclonal

• Clone:

  [8G3B6]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Validation:

  Antibody is Knockout validated.

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 60kDa

• Fragment:

  IgG

• Symbol:

  AKT2

• NCBI Official Name:

  V-akt murine thymoma viral oncogene homolog 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Rac protein kinase beta, Murine thymoma viral (v-akt) homolog-2, RAC-BETA, PRKBB, PKBBETA, HGNC:392, v-akt murine thymoma viral oncogene homolog 2, AKT2, PKBB, HIHGHH

• Tested Applications:

  WB, IHC, ICC, IF, IP, ChIP

• Physical Properties:

  Liquid