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AKT2 Antibody

CAT: 0223-62-605Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-605Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
NCBI Gene ID
208
Swiss Prot
P31751
Accession Number
P31751
Host
Rabbit
Reactivity
Human
Immunogen
This AKT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-123 amino acids from the Central region of human AKT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
AKT2
NCBI Official Name
RAC-beta serine/threonine-protein kinase
NCBI Organism
Homo sapiens
Background Reference 01
Vojtek, A.B., et al., Mol. Cell. Biol. 23 (13) :4417-4427 (2003) .
Background Reference 02
Yuan, Z.Q., et al., J. Biol. Chem. 278 (26) :23432-23440 (2003) .
Background Reference 03
Jones, D.T., et al., Blood 101 (8) :3174-3180 (2003) .
Background Reference 04
Brozinick, J.T. Jr., et al., Diabetes 52 (4) :935-941 (2003) .
Other Product Names
RAC-beta serine/threonine-protein kinase, Protein kinase Akt-2, Protein kinase B beta, PKB beta, RAC-PK-beta, AKT2
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
1170703
Physical Properties
Liquid

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