H2AFV Antibody

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]

• NCBI Gene ID:

  94239

• Swiss Prot:

  Q71UI9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Other

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human H2AFV (NP_036544.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 14kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  H2AFV

• Positive Control 2:

  A-431

• Positive Control 3:

  Mouse thymus

• Positive Control 4:

  Mouse spleen

• Positive Control 5:

  Rat thymus

• Positive Control 6:

  Rat lung

• NCBI Official Name:

  H2A histone family member V

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  H2A.Z-2, H2AV, histone H2A.V, H2A.F/Z, histone H2A.F/Z, purine-rich binding element protein B

• Tested Applications:

  WB

• Physical Properties:

  Liquid