NFAT5 Antibody

• Background:

  The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  10725

• Swiss Prot:

  O94916

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1300 to the C-terminus of human NFAT5 (NP_619728.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction, Transcription

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 174kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  NFAT5

• Positive Control 2:

  A-549

• NCBI Official Name:

  Nuclear factor of activated T cells 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NF-AT5, NFATL1, NFATZ, OREBP, TONEBP, nuclear factor of activated T-cells 5, NFAT-like protein 1, T-cell transcription factor NFAT5, TonE-binding protein, glutamine rich protein H65, nuclear factor of activated T-cells 5, tonicity-responsive, osmotic response element-binding protein, tonicity-responsive enhancer-binding protein

• Tested Applications:

  WB

• Physical Properties:

  Liquid