Products for Research Use Only

NFAT2 Antibody

CAT: 0223-16-027Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-027Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
NCBI Gene ID
4772
Swiss Prot
O95644
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human NFAT2 (NP_765978.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 78kDa
Fragment
IgG
Symbol
NFATC1
Positive Control 2
U-87MG
Positive Control 3
K-562
Positive Control 4
Mouse spleen
NCBI Official Name
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NCBI Organism
Homo sapiens
Other Product Names
Nuclear Factor of Activated T Cells; Cytoplasmic 1; NFAT Transcription Complex Cytosolic Component; NF-ATc1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid