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PON2 Antibody

CAT: 0223-16-615Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-615Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI Gene ID
5445
Swiss Prot
Q15165
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PON2 (NP_000296.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PON2
Positive Control 2
293T
NCBI Official Name
Paraoxonase 2
NCBI Organism
Homo sapiens
Other Product Names
PON2, serum paraoxonase/arylesterase 2, serum aryldialkylphosphatase 2, paraoxonase nirs, paraoxonase 2, aromatic esterase 2, A-esterase 2
Tested Applications
WB
Physical Properties
Liquid

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