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PON1 Antibody

CAT: 0223-55-339Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-339Size:400 µL
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Background
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
NCBI Gene ID
5444
Swiss Prot
P27169
Accession Number
P27169
Host
Rabbit
Reactivity
Human
Immunogen
This PON1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
PON1
NCBI Official Name
Serum paraoxonase/arylesterase 1
NCBI Organism
Homo sapiens
Background Reference 01
Ergun, M.A., et al. Biochem. Genet. (2010) In press :
Background Reference 02
Cagirci, G., et al. J. Heart Valve Dis. 19 (4) :453-458 (2010)
Background Reference 03
Mendonca, M.I., et al. Rev Port Cardiol 29 (4) :571-580 (2010)
Background Reference 04
Hashemi, M., et al. Genet. Mol. Res. 9 (3) :1735-1741 (2010)
Other Product Names
Serum paraoxonase/arylesterase 1, PON 1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
Tested Applications
WB, IHC-P, Flow
Protein ID
308153572
Physical Properties
Liquid

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