PIGP Antibody

• Background:

  This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) . This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described.

• NCBI Gene ID:

  51227

• Swiss Prot:

  P57054

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 25-158 of human PIGP (NP_710148.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 22kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:200 - 1:2000

• Symbol:

  PIGP

• NCBI Official Name:

  Phosphatidylinositol glycan anchor biosynthesis class P

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DCRC, DCRC-S, DSCR5, DSRC, EIEE55, PIG-P, phosphatidylinositol N-acetylglucosaminyltransferase subunit P, Down syndrome critical region gene 5, Down syndrome critical region protein 5, Down syndrome critical region protein C, phosphatidylinositol glycan, class P, phosphatidylinositol-glycan biosynthesis class P protein, phosphatidylinositol-n-acetylglucosaminyltranferase subunit

• Tested Applications:

  WB

• Physical Properties:

  Liquid