Products for Research Use Only
RegisterLogin

PIG3 Antibody

CAT: 0223-60-424Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-60-424Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
9540
Swiss Prot
Q53FA7
Accession Number
Q53FA7
Host
Rabbit
Reactivity
Human
Immunogen
This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TP53I3
NCBI Official Name
Quinone oxidoreductase PIG3
NCBI Organism
Homo sapiens
Background Reference 01
Kotsinas, A., et al. Oncogene 29 (37), 5220 (2010) :
Background Reference 02
Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)
Background Reference 03
Lee, J.H., et al. Oncogene 29 (10) :1431-1450 (2010)
Background Reference 04
Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)
Other Product Names
Quinone oxidoreductase PIG3, 1---, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein, TP53I3, PIG3
Tested Applications
WB
Protein ID
76789665
Physical Properties
Liquid

Related Products

CatalogName
71-172PIGR Antibody
71-171PIGR Antibody
29-354PIGK Antibody
26-194PIGT Antibody
26-135PIGQ Antibody
61-649PIGM Antibody
61-309PIGC Antibody
56-789PIGV Antibody
60-888PIGB Antibody
59-722PIGS Antibody

Alternative Products

CatalogName
abx133645-01PIG3 (PIG3) Antibody
MBS9602202-01PIG3 Antibody
MBS8242030-01Anti-PIG3 Antibody
MBS9244874-01PIG3 Polyclonal Antibody
32988-05111Human PIG3 Antibody
RQ7669PIG3 Antibody / TP53I3
526948-01PIG3

Popular Products