PIGQ Antibody

• Background:

  PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) .This gene is involved in the first step in glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) .

• NCBI Gene ID:

  9091

• Swiss Prot:

  B2RAU6

• Accession Number:

  NP_004195

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PIGQ.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PIGQ antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  65 kDa

• Applications Notes:

  PIGQ antibody can be used for detection of PIGQ by ELISA at 1:312500. PIGQ antibody can be used for detection of PIGQ by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PIGQ

• NCBI Official Name:

  Phosphatidylinositol glycan anchor biosynthesis, class Q

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Martin, J., (2004) Nature 432 (7020), 988-994.

• Other Product Names:

  PIGQ, GPI1, MGC12693, c407A10.1, hGPI1

• Tested Applications:

  ELISA, WB

• Protein ID:

  22538450

• Physical Properties:

  Liquid