PABPC1 Antibody

• Background:

  This gene encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

• NCBI Gene ID:

  26986

• Swiss Prot:

  P11940

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC1 (NP_002559.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 71kDa

• Fragment:

  IgG

• Symbol:

  PABPC1

• Positive Control 2:

  HT-29

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Rat lung

• NCBI Official Name:

  Poly (A) binding protein, cytoplasmic 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PABPC1, PAB1, PABP, PABP1, PABPC2, PABPL1

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid