KLRC4 Antibody

• Background:

  Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member.

• NCBI Gene ID:

  8302

• Swiss Prot:

  O43908

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-55 of human KLRC4 (NP_038459.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Innate Immunity

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 14kDa

• Fragment:

  IgG

• Symbol:

  KLRC4

• Positive Control 2:

  NCI-H460

• Positive Control 3:

  293T

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Rat kidney

• NCBI Official Name:

  Killer cell lectin like receptor C4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NKG2-F, NKG2F, NKG2-F type II integral membrane protein, NK cell receptor F, NKG2-F-activating NK receptor, killer cell lectin-like receptor subfamily C, member 4, natual killer cell group 2-F

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid