KLRC1 Antibody

• Background:

  Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

• NCBI Gene ID:

  3821

• Swiss Prot:

  P26715

• Accession Number:

  P26715

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KLRC1

• NCBI Official Name:

  NKG2-A/NKG2-B type II integral membrane protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Brooks, A.G., et.al., J. Exp. Med. 185 (4), 795-800 (1997)

• Background Reference 02:

  Plougastel, B., et.al., Immunogenetics 44 (4), 286-291 (1996)

• Other Product Names:

  NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159a, KLRC1, NKG2A

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  317373399

• Physical Properties:

  Liquid