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ASGR1 Antibody

CAT: 0223-14-884Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-14-884Size:100 µL
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Background
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
432
Swiss Prot
P07306
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ASGR1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ASGR1
Positive Control 2
22Rv1
Positive Control 3
SW620
Positive Control 4
Mouse liver
Positive Control 5
Mouse lung
Positive Control 6
Mouse testis
NCBI Official Name
Asialoglycoprotein receptor 1
NCBI Organism
Homo sapiens
Other Product Names
ASGR1, HL-1, ASGPR, ASGPR1, CLEC4H1
Tested Applications
WB
Physical Properties
Liquid

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