ASGR2 Antibody

• Background:

  ASGR2 binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.

• NCBI Gene ID:

  23253

• Swiss Prot:

  P07307

• Accession Number:

  NP_001172

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASGR2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10410 - Fetal Lung Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ASGR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  35 kDa

• Applications Notes:

  ASGR2 antibody can be used for detection of ASGR2 by ELISA at 1:312500. ASGR2 antibody can be used for detection of ASGR2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ANKRD12

• NCBI Official Name:

  Ankyrin repeat domain 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yik, J.H., et al., (2002) J. Biol. Chem. 277 (43), 40844-40852.

• Other Product Names:

  ASGR2, ANCO1, GAC-1, ANCO-2, Nbla00144

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4502253

• Physical Properties:

  Liquid