BDNF Antibody

• Background:

  This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

• NCBI Gene ID:

  627

• Swiss Prot:

  P23560

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-247 of human BDNF (NP_733928.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Growth Factors, Neuroscience, Obesity

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 14kDa

• Fragment:

  IgG

• Symbol:

  BDNF

• Positive Control 2:

  SW480

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Rat brain

• NCBI Official Name:

  Brain-derived neurotrophic factor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BDNF , brain-derived neurotrophic factor, MGC34632, neurotrophin

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid