CDK11B Antibody

• Background :

  This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  984

• Swiss Prot :

  P21127

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  HeLa

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 110kDa

• Fragment :

  IgG

• Symbol :

  CDK11B

• Positive Control 2 :

  Mouse brain

• NCBI Official Name :

  Cyclin dependent kinase 11B

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CDC2L1, CDK11, CDK11-p11CDK11-p46, CDK11-p58, CLK-1, PITSLREA, PK58, p58, p58CDC2L1, p58CLK-1, cyclin-dependent kinase 11B, CDC-related protein kinase p58, PITSLRE serine/threonine-protein kinase CDC2L1, cell division cycle 2-like 1 (PITSLRE proteins), cell division protein kinase 11B, galactosyltransferase-associated protein kinase p58/GTA, p58 CLK-1

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid