SHMT2 Antibody

• Background:

  This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  6472

• Swiss Prot:

  P34897

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 265-504 of human SHMT2 (NP_005403.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 52kDa

• Fragment:

  IgG

• Symbol:

  SHMT2

• Positive Control 2:

  OVCAR3

• Positive Control 3:

  22Rv1

• Positive Control 4:

  Mouse liver

• Positive Control 5:

  Mouse kidney

• NCBI Official Name:

  Serine hydroxymethyltransferase 2 (mitochondrial)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SHMT2, GLYA, SHMT, HEL-S-51e

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid